Comparison of pre-extubation propofol and midazolam to prevent emergence agitation in children—a prospective randomized study

Abstract Background Emergence delirium is one of the most common and troublesome complications seen after inhalational anesthesia, with an estimated 20–80% incidence rate. It can lead to increase in mortality, morbidity, hospital stay, which indirectly reflects a major economic burden. The aim our study compare effect propofol two different doses midazolam prevent emergence agitation children given 5 min before extubation. Seventy-five ASA (American Society Anesthesiologists) Physical Status I–II patients aged 2–14 years who were scheduled for elective surgeries under general anesthesia included study. Patients groups randomized into three 25 each group; group P (propofol 0.5 mg/kg iv), ML (midazolam low dose 0.03 M 0.05 iv) primary objective was prevention children. secondary observe like bronchospasm, laryngospasm, persistent cough, desaturation pediatric patients. Results time taken from surgery 5.11 ± 1.223 8.53 2.326 12.45 2.145 min, respectively, found be statistically significant. observed Cole score >3 14 (56%) P, 7 (28%), 6 (24%) M, respectively. Conclusions Midazolam extubation effective preventing during postoperative period without delay recovery anesthesia.